- Activate EARLY in head injury patients on warfarin.
- Order on EPR & Paper [see below]
- Infuse over no more than 30 min
- Recheck INR at 30 min after finished infusion
Indications
- EMERGENCY reversal of Warfain
- Factor II or X deficiency
Contraindications/Cautions
- Allergy
- DIC
- Previous HIT (heparin induced thrombocytopenia) • High risk Thrombosis
- Recent MI
- Decompensated Liver disease
- Pregnancy
- Sepsis
Requesting
- Request from Haematology On-Call [This can happen before CT]
- Weight [Estimate if unknown]
- INR/Clotting required
Prescribing Octaplex on EPR
Requests & Care Plans OR Quick Orders- Search: Blood Components
- Coag Factors select YES
- Coag Factor product and units free text Octaplex & Dose
- Complete ALL mandatory fields
- To collect & give Octaplex the [Paper] Transfusion Care Pathway must also be completed
UNSURE if your patient has received OCTAPLEX DON’T ASSUME. Check transfusion have dispensed it!
Giving
- Typically 2000-3000units (Haematologist will give the dose)
- Each 500units made up to 20ml (blue colour)
- 1st 5min 1ml per min (Observing for allergy)
- Then increase rate by 1ml per min (every 1-2 min) o Maximum rate 8ml per min
Full dose is typically given within 30min
Monitoring
- Repeat Clotting at 20-30min post infusion
- Inadequate responce discuss with Haematologist
PDF:octaplex
