Category: Medical

Acidosis & VBG’s

We are frequently asked to check the lactate on Venous Blood Gases (VBG’s), by the nursing staff. However, remember to look at the first result (pH) it is the most important.

Acidosis: Unless you have a good reason (e.g. you know its due to DKA) you should be investigating and performing an Arterial Blood Gas (ABG)

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Parkinson’s Disease & can’t swallow

We all recognise the importance of ensuring patients with Parkinson’s disease (PD) get their medication, but..

What do you do if the patient can’t swallow?

We will need to work out what alternative routes we could use, for example dispensable via NG or patches, and what dose. For an ED clinical it is most likely beyond us and we need help! However, that may be extremely difficult to get especially Out of Hours

https://www.parkinsonscalculator.com/calculator2-withoutNG.htmlpdmedcalc

Excellent website that can give you options – select the patients normal regime (initially just one line but you can add as many as needed) and press calculate.  It gives you a dispensable and patch dose, which can help the discussion with pharmacy about where we can get it

Pulmonary Embolism in Pregnancy

Unfortunately the the normal pathway for investigation of PE performs poorly in pregnancy RCOG have the following pathway

1. Investigation – of suspected PE

  • Clinical assessment – its all on the history and exam scoring doesn’t work
  • Perform the following tests:
    • CXR – sheilding can protect the baby and may avoid further radiation
    • ECG
    • Bloods: FBC, U&E, LFTs, Clotting
  • Commence Tinzaparin (unless treatment is contraindicated – use booking weight to calculate dose) –[BNF]

 

Hypoglycaemia – Adult

Hypoglycaemia (Blood glucose under 4.0 mmol/l) is potentially fatal and should be treated. it may be defined as “mild” self-treated, or “severe” treated by a third party i.e. you.

Hypoglycaemia is a common side-effect of insulin and sulfonylureas (they start with gli-) as they both work by lowering glucose concentration in the blood. Other diabetic medications work by preventing glucose rise, thus posing a lesser risk.

 

Signs & Symps

  • Autonomic: Sweating, Palpitations, Shaking, Hunger
  • Neuroglycopenic: Confusion, Drowsy, Odd behaviour, Incoordination, Speech difficulty
  • General: Nausea, Headache

Risk Factors

  • Medical: 
    • Diabetic: Strict control, Long term Insulin, Lipohypertrophy at injection sites,Impaired awareness of hypoglycaemia
    • Organ dysfunction: Severe hepatic dysfunction, Renal impairment, Cognitive dysfunction/dementia, Endocrine (Addisons, hypothyroid, hypopituitary)
    • GIT: Gastroenteritis, impaired absorption, Bariatric surgery
    • Medication: Concurrent use of medicines with hypoglycaemic agents e.g. warfarin, quinine, salicylates, fibrates, sulphonamides (including cotrimoxazole), monoamine oxidase inhibitors, NSAIDs, probenecid, somatostatin analogues, SSRIs.
    • Sepsis
    • Terminal illness
  • Lifestyle:
    • Reduced/Irregular intake: Poor diet, Irregular lifestyle, Alcohol
    • Increased use: Exercise (relative to usual), Early pregnancy, Breast feeding
    • Poor control: Increasing age, No or inadequate blood glucose monitoring, Alcohol

Treatment

Conscious & Orientated

  1. 15-20g fast acting glucose
    • 4-5 jelly babies
    • 3-4 heaped teaspoons of sugar dissolved in water (milk delays absorption)
    • 150-200ml fresh fruit juice
  2. Rpt Blood Glucose 10-15min
    • if blood glucose remains <4.0mmol/l step one may be repeated up to 3 times in total
  3. Blood Glucose remains <4.0mmol/l
    • 150-200ml 10% Glucose IV
    • 1mg Glucogon IM (if starved or sulfonylureas may not work well)
  4. Blood Glucose >4.0mmol/l – Give long acting Carbs
    • 2 Biscuits
    • 1 Slice bread/toast
    • 200-300ml milk (not soya)
    • Meal
  5. Don’t omit insulin injections
  6. Diabetic review: most patients can be followed up by diabetic nurses but some may need admission.
  7. Patient Advice Sheet

Conscious but agitated, confused, unable to cooperate

  • If patient CAN cooperate – follow guide above
  • If patient CAN’T cooperate
    • 1.5 -2 tubes 40% glucose gel (Glucogel) squeezed into the mouth between the teeth and gums (can be substituted for step 1 above)
    • 1mg Glucogon IM (if starved or sulfonylureas may not work well)
    • Follow subsequent steps as above

Unconscious, seizures, very aggressive

Start at step 3 above (while managing ABC), the choice of whether to use IV glucose or IM glycogen will be determined by practicality of achieving IV/IO access.

Although you will need to follow the remaining steps the patient will almost certainly require admission.

 

Reference

Patient Advice Sheet – Hypo’s

Joint British Diabetic Society – The Hospital Management of Hypoglycaemia in Adults with Diabetes Mellitus 3rd edition